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Iodixanol-Induced Hypersensitivity During Coronary Intervention: A Case Report

1, 1, 1, 2, 3

  1. 1Doctor of Pharmacy, Department of Pharmacy Practice, Bangalore Baptist Hospital, Bengaluru, Karnataka, INDIA.
  2. 2MBBS, MD-Internal Medicine, DM-Cardiology, Bangalore Baptist Hospital, Bengaluru, Karnataka, INDIA.
  3. 3Department of Pharmacy Practice, Head of Department, Karnataka College of Pharmacy, Bengaluru, Karnataka, INDIA.

CORRESPONDENCE

Kumar Masum

Doctor of Pharmacy, Department of Pharmacy Practice, Bangalore Baptist Hospital, Bengaluru, Karnataka, INDIA.

masumkumar412@gmail.com

Received: 16-04-2026; Accepted: 27-07-2026.

Volume 19, Issue 4 · pp. 554-556 · 2026 · DOI: 10.5530/ijopp.20260824

ABSTRACT

Iodinated contrast media, such as Iodixanol (Visipaque®), are dyes used to improve the clarity of blood vessels and organs during imaging procedures. Iodixanol is a non-ionic, iso-osmolar agent designed to be safer and better tolerated than older contrast dyes. We describe the case of a 48-year-old man with diabetes, high blood pressure, a past stroke, and a seizure disorder who presented with chest pain and was diagnosed with Acute Coronary Syndrome - Anterolateral Wall Myocardial Infarction. He underwent a heart procedure on the left anterior descending artery using Iodixanol. Soon after the dye was given, he developed itching, swelling around the eyes, and red raised patches on the skin, showing an allergic reaction with urticaria and angioedema. He was treated with intravenous antihistamines and steroids, and his symptoms improved. This case highlights that even safer contrast dyes like Iodixanol can cause allergic reactions, stressing the need for close monitoring and timely management.

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    MS, D., Roy, S., Masum, K., Srinivas, S., & Ramaiah, B. (2026). Iodixanol-Induced Hypersensitivity During Coronary Intervention: A Case Report. Indian Journal of Pharmacy Practice, 19(4), 554-556. https://doi.org/10.5530/ijopp.20260824

    Copyright and licence

    © 2026 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC BY 4.0