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Sjögren’s Syndrome–Vasculitis: Azathioprine Induced Myelosuppression–A Case Report

1, 2, 2, 3

  1. 1Department of General Medicime Rohini Super Speciality Hospital, Hanamkonda, Warangal – 506 001, Telangana State, INDIA.
  2. 2Department of Pharmacy Practice, Rohini Super Speciality Hospital, and St.Peter’s Institute of Pharmaceutical Sciences, Hanamkonda, Warangal – 506 001, Telangana State, INDIA.
  3. 3Department of Pharmacy Practice St.Peter’s Institute of Pharmaceutical Sciences, Hanamkonda, Warangal – 506 001, Telangana State, INDIA.

CORRESPONDENCE

Vatipelli Mahender

Department of Pharmacy Practice St.Peter’s Institute of Pharmaceutical Sciences, Hanamkonda, Warangal – 506 001, Telangana State, INDIA.

mahendra.v@stpeters.in

Volume 9, Issue 3 · pp. 206-209 · 2016 · DOI: 10.5530/ijopp.9.3.14

ABSTRACT

Sjögren's syndrome is a chronic autoimmune disease causing destruction of exocrine glands, due to lymphocytic infiltration predominately affects middle age women. Sjogren's syndrome classified may be either primary or secondary Sjogren's syndrome. The prevalence of primary Sjögren's syndrome is approximately 0.5–1.0%, while 30% of patients with autoimmune rheumatic diseases suffer from secondary Sjögren's syndrome. Treatment focuses on relief of the symptoms affecting particular areas of the body. Glucocorticoids (Prednisolone) and/ or immunosuppressive agents (azathioprine) are indicated for the treatment of systemic vasculitis. In this case, the patient is suffering from Sjogren’s syndrome and patient was prescribed with a glucocorticoid and an immunosuppressive agent (azathioprine). Use of Azathioprine has lead to myelosuppression. So, the dosing schedule of these drugs are important and dosing of drug should be done according to the patient response and at the same time check for adverse effects during course of treatment and any altered lab parameters.

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    Reddy, K. B., priya, B. V., Navya, B., & Mahender, V. (2016). Sjögren’s Syndrome–Vasculitis: Azathioprine Induced Myelosuppression–A Case Report. Indian Journal of Pharmacy Practice, 9(3), 206-209. https://doi.org/10.5530/ijopp.9.3.14

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    © 2016 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC BY 4.0