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A Case Report on Capecitabine Induced Hand Foot Syndrome and Mucositis

1, 1, 2

  1. 1Department of Pharmacology, Government Medical College Calicut- 673008, Kerala, India.
  2. 2Department of Pharmacy Practice, Annamalai University, Chidambram-608002, Tamil Nadu, India.

CORRESPONDENCE

Ponni Jothi Prakasam

Department of Pharmacology, Government Medical College Calicut- 673008, Kerala, India.

ponnij87@yahoo.co.in

Volume 7, Issue 4 · pp. 46-49 · 2014 · DOI: 10.5530/ijopp.7.4.9

ABSTRACT

Hand foot syndrome (HFS) is a dose-limiting toxicity of Capecitabine. Though HFS is not life threatening, it can affect the daily activities and quality of life of a patient. Proper patient education aids in early detection of HFS and in minimizing or preventing the harm caused by it. We report a case of an elderly male patient who received adjuvant chemotherapy with Capecitabine for advanced Gastric carcinoma. While on treatment, he developed signs and symptoms consistent with Capecitabine induced grade 2 HFS and oral mucositis. The adverse drug reaction causality assessment done using the WHO scale showed a ‘Probable’ association of the reaction with Capecitabine.

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    Prakasam, P. J., Krishnan, D. G., & Mohanta, G. P. (2014). A Case Report on Capecitabine Induced Hand Foot Syndrome and Mucositis. Indian Journal of Pharmacy Practice, 7(4), 46-49. https://doi.org/10.5530/ijopp.7.4.9

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    © 2014 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC BY 4.0