Nitrofurantoin Induced Reversible Interstitial Lung Disease
1, 2
- 1Department of Clinical Pharmacy, Aster Mims Hospital, Kannur, Kerala, INDIA..
- 2Department of Critical Care Medicine, Aster Mims Hospital, Kannur, Kerala, INDIA..
CORRESPONDENCE
Shabana AshrafDepartment of Clinical
Pharmacy, Aster Mims Hospital, Kannur, Kerala, INDIA..
Received: 04-05-2023; Accepted: 11-07-2023.
Volume 16, Issue 4 · pp. 366-368 · 2023 · DOI: 10.5530/ijopp.16.4.63
ABSTRACT
Drug-induced interstitial lung disease is an increasingly common cause of morbidity and mortality. Nitrofurantoin is a broad-spectrum antibiotic used for acute uncomplicated or simple cystitis as well as for prophylaxis of recurrent infection. We recently encountered a case of Nitrofurantoin-induced interstitial lung disease in an elderly patient who was on Nitrofurantoin for a year and a half for recurrent urinary tract infections. On further evaluation, she was diagnosed with drug-induced interstitial lung disease, which was confirmed by radiographic evidence. Nitrofurantoin was discontinued and managed with low-dose systemic glucocorticoids. This case report highlights the need for close vigilance of pulmonary toxicities in patients taking long-term Nitrofurantoin therapy.
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Ashraf, S., & Salahudheen, S. (2023). Nitrofurantoin Induced Reversible Interstitial Lung Disease. Indian Journal of Pharmacy Practice, 16(4), 366-368. https://doi.org/10.5530/ijopp.16.4.63
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© 2023 Author(s)
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