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A Study on Antimicrobial Evaluation of Different Generic and Branded Tablet of Ciprofloxacin HCl Marketed in Wardha District

1, 2, 1

  1. 1Department of Pharmaceutical Chemistry, Institute of Pharmacy and Research, Badnera, Amravati, Maharashtra, INDIA.
  2. 2Department of Pharmaceutics, Institute of Pharmacy and Research, Badnera, Amravati, Maharashtra, INDIA.
  3. 3Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha, Maharashtra, INDIA.

CORRESPONDENCE

Shramika A Chore

Department of Pharmaceutics Institute of Pharmacy and Research, Badnera, Amravati, Maharashtra, INDIA.

shramikachore16@gmail.com

Volume 15, Issue 3 · pp. 177-183 · 2022 · DOI: 10.5530/ijopp.15.3.34

ABSTRACT

Bacterial infection is responsible for various activity including respiratory, urinary tract, gastrointestinal and abdominal infections. Ciprofloxacin HCl, a second-generation fluroquinolone antibiotic that can treat a number of bacterial infections. The aim of this work was to evaluate antimicrobial activity of different generic and branded drug formulation marketed in Wardha district. i.e. Cifran and Zoxan. All the formulations obtained from the market were in compliance with the control samples in respect of Preformulation study, Disintegration,in vitrodrug release, and antimicrobial potential. Thus, the antimicrobial activity of marketed and control sample was also same shows satisfactory results againstStaphylococcus aureusas compare toEscherichia coli,butStaphylococcus aureuswas shows better microbiological assay response as compare toE. coli.

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    Dighade, S. J., Chore, S. A., & Gaurkar, S. D. (2022). A Study on Antimicrobial Evaluation of Different Generic and Branded Tablet of Ciprofloxacin HCl Marketed in Wardha District. Indian Journal of Pharmacy Practice, 15(3), 177-183. https://doi.org/10.5530/ijopp.15.3.34

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    © 2022 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC BY 4.0