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Review

The Role of Finasteride in the Management of Androgenetic Alopecia in Male: A Narrative Review

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  1. 1School of Pharmacy, International Medical University, Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur, MALAYSIA.

CORRESPONDENCE

Anil Tumkur

School of Pharmacy, International Medical University, Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur, MALAYSIA.

pharmacistanil@gmail.com

Volume 13, Issue 1 · pp. 3-13 · 2020 · DOI: 10.5530/ijopp.13.1.2

ABSTRACT

The purpose of this review was to evaluate the role of finasteride, a type-II 5α-reductase inhibitor in the prevention and treatment of androgenetic alopecia (AGA) in males. Finasteride inhibits 5α-reductase and reduce the biosynthesis of dihydrotestosterone (DHT). This inhibition marks a decrease in concentration of DHT and provides a novel and selective approach to androgen deprivation. Clinical trials have proven the safety and efficacy of tablet finasteride 1 mg for AGA. In this review, we discuss all aspects of finasteride, including dosing and indication, pharmacology, pharmacokinetics to its role in the treatment of AGA.

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    Tumkur, A., Ern, C. C. T. C., Shuang, C. C., Yong, A. C. H., Yee, C. P., Leen, C. T., Lock, L. K., & Singh, N. (2020). The Role of Finasteride in the Management of Androgenetic Alopecia in Male: A Narrative Review. Indian Journal of Pharmacy Practice, 13(1), 3-13. https://doi.org/10.5530/ijopp.13.1.2

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    © 2020 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC BY 4.0